Omega-3s anti-inflammatory mechanism revealed
Omega-3s may reduce inflammation by acting on a receptor found in fat tissue and on inflammatory immune cells called macrophages, according to research.
The new research published in the journal Cell, suggests the mechanisms behind omega-3’s actions as an anti-onflammatory are due to its action on G-protein-coupled receptor 120 (GPR120) working as an omega-3 FA receptor/sensor.
“Omega-3s are very potent activators of GPR120 on macrophages – more potent than any other anti-inflammatory we’ve ever seen,” said lead researcher Dr Jerrold Olefsky of the University of California, San Diego.
